The Broads made a founding gift of $100 million and the Broad Institute was formally launched in May 2004. To create a new organization that was open, collaborative, cross-disciplinary and able to organize projects at any scale, planning took place in 2002–2003 among philanthropists Eli and Edythe Broad, MIT, the Whitehead Institute, Harvard and the Harvard-affiliated hospitals (in particular, the Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Children's Hospital Boston, the Dana–Farber Cancer Institute and the Massachusetts General Hospital). It facilitated small molecule screening projects for more than 80 research groups worldwide. Its screening facility was one of the first high-throughput resources opened in an academic setting. Another cornerstone was the Institute of Chemistry and Cell Biology established by Harvard Medical School in 1998 to pursue chemical genetics as an academic discipline. As early as 1995, scientists at the Whitehead started pilot projects in genomic medicine, forming an unofficial collaborative network among young scientists interested in genomic approaches to cancer and human genetics. Founded in 1982, the Whitehead became a major center for genomics and the Human Genome Project. One cornerstone was the Center for Genome Research of Whitehead Institute at MIT.

The Broad Institute evolved from a decade of research collaborations among MIT and Harvard scientists. The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it partners with the Massachusetts Institute of Technology, Harvard University, and the five Harvard teaching hospitals.īroad Institute, 415 Main St. Broad Institute of MIT and Harvard (IPA: / b r oʊ d/, pronunciation respelling: BROHD), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States.

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